Zesty Garlic Butter Shrimp Scampi Lasagna Recipe for Seafood Lovers

Crafting a mind-blowing garlic butter shrimp scampi lasagna combines two classic favorites into one incredible dish that will leave you speechless.

Layers of tender pasta sheets embrace succulent seafood and rich, creamy sauce.

Cheesy goodness mingles with delicate shrimp, creating a meal that feels both luxurious and comforting.

Mediterranean flavors dance across each bite, promising an unexpected culinary adventure.

Delicate herbs and garlic infuse every layer with incredible depth and complexity.

Bold ingredients come together in a symphony of textures and tastes.

Prepare to wow your dinner guests with this innovative twist on traditional Italian cuisine.

Garlic Butter Shrimp Scampi Lasagna Explained

  • Dive into Delicious Fusion: Combine classic Italian lasagna with succulent garlic butter shrimp for a mouthwatering twist that breaks traditional recipe boundaries.
  • Master Gourmet Cooking at Home: Create a restaurant-quality dish with straightforward steps that make you feel like a professional chef without intimidating kitchen skills.
  • Perfect for Crowd-Pleasing Meals: Impress dinner guests or family members with a luxurious main course that looks complicated but comes together surprisingly easily.
  • Versatile Dinner Solution: Enjoy a complete meal in one dish that balances protein, pasta, and creamy sauce, making meal planning and preparation a breeze.

Ingredients for Garlic Butter Shrimp Lasagna

Main Ingredients:
  • Shrimp: Fresh seafood that provides the primary protein for this lasagna dish.
  • Lasagna Noodles: Classic pasta sheets that form the structural base of the lasagna.
  • Ricotta Cheese: Creamy cheese that adds richness and texture to the layers.
  • Mozzarella Cheese: Melty cheese that creates a stretchy, gooey topping.
Dairy Components:
  • Parmesan Cheese: Sharp cheese that enhances the sauce's depth of flavor.
  • Heavy Cream: Luxurious dairy product that creates a smooth, rich sauce.
Sauce and Seasoning Ingredients:
  • Garlic, Red Pepper Flakes, Salt, Pepper: Aromatic and flavorful seasonings that add depth to the dish.
  • Olive Oil, Butter: Cooking fats that provide rich flavor and help create the sauce.
  • Chicken Broth, White Wine: Liquid components that add complexity to the garlic butter sauce.
Garnish:
  • Fresh Parsley: Bright herb that adds a fresh finishing touch to the lasagna.

Instructions for Shrimp Scampi Lasagna

Step 1: Prepare Oven and Noodles

Crank up your oven to a toasty 375°F (190°C). Boil lasagna noodles according to package directions until perfectly tender.

Drain and set aside, ready for layering.

Step 2: Sizzle the Shrimp

Warm olive oil in a large skillet over medium heat.

Toss in the shrimp and cook until they transform into a beautiful pink color and are fully cooked, about 2-3 minutes per side. Transfer the succulent shrimp to a separate plate.

Step 3: Create Garlic Butter Magic

In the same skillet, melt butter over medium heat. Add minced garlic and cook until it releases its aromatic charm, roughly 1 minute.

Step 4: Develop the Luxurious Sauce

Introduce these ingredients to create a dreamy sauce:
  • Red pepper flakes
  • White wine (optional)
  • Heavy cream
  • Chicken broth

Bring the mixture to a gentle simmer and let it bubble away for 3-5 minutes until it thickens slightly.

Step 5: Finish the Sauce

Remove from heat and fold in Parmesan cheese until it melts into a smooth, creamy consistency.

Season with salt and pepper to your taste.

Step 6: Layer the Lasagna

In a 9×13-inch baking dish, spread a thin layer of garlic butter sauce on the bottom.

Create three layers, each consisting of:
  • Lasagna noodles
  • Cooked shrimp
  • Ricotta cheese
  • Mozzarella cheese
  • Garlic butter sauce

Step 7: Bake to Perfection

Cover the dish with foil and bake for 25 minutes. Remove the foil and continue baking for 10-15 minutes until the cheese becomes bubbly and turns a gorgeous golden color.

Step 8: Serve and Garnish

Sprinkle fresh chopped parsley over the top just before serving. Slice and enjoy your decadent seafood lasagna masterpiece!

Tips for Creamy Garlic Butter Shrimp Lasagna

  • Choose medium-sized, deveined shrimp for consistent cooking and easier eating experience.
  • Pat shrimp dry before cooking to reduce excess moisture and ensure sauce stays thick and creamy.
  • Add a splash of lemon juice to the garlic butter sauce for a bright, zesty undertone that complements the seafood.
  • Adjust red pepper flakes based on personal heat preference, starting with a small amount and increasing gradually.
  • Let lasagna rest for 10 minutes after baking to allow cheese to set and make slicing easier.

Creative Twists for Shrimp Scampi Lasagna

Seafood Fusion Variations:
  • Crab Coastal Remix: Replace shrimp with lump crab meat for a luxurious seafood experience.
  • Scallop Mediterranean Style: Swap shrimp with tender sea scallops for a delicate protein alternative.
  • Vegetarian Comfort Edition: Substitute shrimp with roasted zucchini and artichoke hearts for a plant-based version.
  • Gluten-Free Friendly Option: Use gluten-free lasagna noodles and ensure all ingredients are certified gluten-free for those with dietary restrictions.

Best Pairings for Shrimp Scampi Lasagna

  • Sauvignon Blanc or Pinot Grigio perfectly complement the garlic butter shrimp's delicate flavors, cutting through the rich creamy sauce with their bright, zesty notes.
  • Fresh arugula salad with lemon vinaigrette provides a peppery, acidic contrast to the lasagna's creamy texture, balancing the dish's richness and adding refreshing complexity.
  • Toasted sourdough or ciabatta bread helps soak up the extra garlic butter sauce, enhancing the meal's overall flavor profile and providing a delightful textural counterpoint.

Storage Advice for Shrimp Scampi Lasagna

  • Store leftover lasagna in an airtight container within 2 hours of cooking. Keep in the refrigerator for up to 3-4 days.
  • Wrap tightly in plastic wrap and aluminum foil. Place in a freezer-safe container and store for up to 2 months. Label with the date.
  • Place a single serving on a microwave-safe plate. Cover with a damp paper towel to prevent drying. Heat in 30-second intervals, stirring between each, until thoroughly warm.
  • Preheat oven to 350F. Cover lasagna with foil to prevent burning. Warm for 15-20 minutes until heated through. Remove foil for the last 5 minutes to crisp the top.

FAQs

  • Can I use frozen shrimp for this recipe?

Yes, you can use frozen shrimp. Just thaw them completely and pat dry before cooking to ensure they cook evenly and don’t release excess water.

  • Is it okay to skip the white wine?

Absolutely. You can replace the white wine with additional chicken broth or use a splash of lemon juice to maintain the flavor profile.

  • How do I prevent the lasagna from becoming watery?

Make sure to drain the shrimp and pat them dry before adding to the dish. Also, avoid overcooking the shrimp, which can release excess moisture.

  • Can I make this recipe ahead of time?

Yes, you can assemble the lasagna up to a day in advance and refrigerate. Just add an extra 10-15 minutes to the baking time if cooking directly from the refrigerator.

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Garlic Butter Shrimp Scampi Lasagna Recipe


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4.5 from 20 reviews

  • Total Time: 1 hour
  • Yield: 6 1x

Description

Garlic butter shrimp scampi lasagna merges coastal Italian flavors with classic comfort food, creating a luxurious pasta experience. Creamy layers of shrimp, garlic, and herbs promise a delightful culinary journey you won’t soon forget.


Ingredients

Scale

Main Ingredients:

  • 9 lasagna noodles
  • 1 pound (454 grams) shrimp, peeled and deveined
  • 2 cups (480 milliliters) mozzarella cheese, shredded
  • 1 cup (240 milliliters) Parmesan cheese, grated
  • 1/2 cup (120 milliliters) ricotta cheese

Seafood and Sauce Ingredients:

  • 1/2 cup (120 milliliters) unsalted butter
  • 6 cloves garlic, minced
  • 1/2 cup (120 milliliters) white wine (optional)
  • 1 cup (240 milliliters) heavy cream
  • 1 cup (240 milliliters) chicken broth
  • 2 tablespoons olive oil

Seasonings and Garnish:

  • 1/4 teaspoon crushed red pepper flakes
  • 2 tablespoons fresh parsley, chopped
  • Salt and pepper to taste

Instructions

  1. Prepare lasagna noodles according to package directions, then drain and set aside at room temperature.
  2. Sauté shrimp in olive oil over medium heat until they turn pink and are fully cooked, approximately 2-3 minutes per side. Transfer cooked shrimp to a separate plate.
  3. In the same skillet, melt butter and add minced garlic, cooking until aromatic for about 1 minute.
  4. Create the sauce by incorporating red pepper flakes, white wine, heavy cream, and chicken broth. Simmer for 3-5 minutes until the mixture slightly thickens.
  5. Remove sauce from heat and blend in Parmesan cheese until smooth and fully incorporated. Season with salt and pepper.
  6. Preheat oven to 375°F (190°C). Spread a thin layer of garlic butter sauce on the bottom of a 9×13-inch baking dish.
  7. Construct first layer by placing lasagna noodles over the sauce, then evenly distribute one-third of the shrimp, ricotta, mozzarella, and garlic butter sauce.
  8. Repeat layering process two more times, ensuring even distribution of ingredients.
  9. Cover the dish with aluminum foil and bake for 25 minutes.
  10. Remove foil and continue baking for an additional 10-15 minutes until cheese becomes golden and bubbling.
  11. Garnish with freshly chopped parsley before serving.

Notes

  • Choose quick-cooking shrimp to prevent overcooking and maintain tender texture during the baking process.
  • Replace heavy cream with half-and-half or whole milk for a lighter version of the dish without sacrificing richness.
  • Toast red pepper flakes briefly in the butter before adding other ingredients to enhance their smoky, spicy flavor profile.
  • Select high-quality Parmesan cheese and freshly grate it for maximum melting and flavor integration in the sauce.
  • Prep Time: 20 minutes
  • Cook Time: 40 minutes
  • Category: Lunch, Dinner
  • Method: Baking
  • Cuisine: Italian

Nutrition

  • Serving Size: 6
  • Calories: 370 kcal
  • Sugar: 1 g
  • Sodium: 480 mg
  • Fat: 26 g
  • Saturated Fat: 14 g
  • Unsaturated Fat: 11 g
  • Trans Fat: 0.5 g
  • Carbohydrates: 16 g
  • Fiber: 1 g
  • Protein: 25 g
  • Cholesterol: 130 mg
Mike Reynolds

Mike Reynolds

Founder & Recipe Developer

Expertise

Farm-to-table cuisine, Seasonal recipe development, Sustainable cooking techniques, Food photography

Education

Asheville-Buncombe Technical Community College (A-B Tech)
Associate Degree in Culinary Arts

Mike studied culinary arts with a strong focus on farm-to-table principles and sustainable cooking. His training emphasized the importance of fresh, local ingredients and environmentally responsible practices in the kitchen.


Mike’s food journey began deep in the Blue Ridge Mountains, where weekends at farmers’ markets and home-cooked meals sparked a lifelong obsession with simple, seasonal eating.
After earning his Associate Degree in Culinary Arts from Asheville-Buncombe Technical Community College, he set out to bring farm-to-table cooking into everyday kitchens, without the fuss.
Mike’s philosophy is all about keeping it fresh, unfussy, and full of heart. When he’s not crafting new single-serving recipes, he’s hiking mountain trails, chatting with local farmers, or experimenting with wild ingredients in his backyard kitchen.

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